Whom it may be suitable for: Can be ideal for the elderly because of fewer side effects when prescribed at lower doses.

Side effects: Jitteriness, insomnia, headaches, dry mouth, nausea (and, rarely, risk of seizure).

Whom it may be suitable for: Not an ideal first-line treatment: Start-up can be difficult to tolerate, and serotonin is often needed to effect mood change.

This article was originally titled "The pros and cons of some popular antidepressants," in the September 2008 issue of Best Health Magazine.

I have problems with panic attacks and have tried Buspar and Effexor.

I asked my doctor which of the newer antidepressants was the most sedating.

She said that they all make claims to be; however, she didn't know. Doug, Remeron and Serzone would appear to be the most sedating new antidepressants available.

Whom it may be suitable for: Those whose depression causes fatigue; also ideal for anxiety symptoms and anxiety disorders; not ideal where weight gain is a health concern.

Pros: Some find this SSRI has the fewest side effects.

Whom it may be suitable for: Those with milder or chronic cases of depression, because it has fewer side effects.

Pros: This norepinephrine dopamine reuptake inhibitor (NDRI) is often added on to other antidepressant treatments that lose effectiveness over time or cause sexual dysfunction.

Paxil probably has the most sedative effects among the SSRIs.