Despite her condition, the couple were still motivated to have a baby, so they continued with the egg retrieval and found a surrogate.

On October 17, 2011, during an interview on Today, Rancic announced she had been diagnosed with early stage breast cancer, for which she would be treated with a double lumpectomy, followed by radiation. She was also featured in People magazine's 100 Most Beautiful of 2006 issue.

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She underwent surgery in mid-October 2011 and returned to work at E! Giuliana was nominated Favorite TV Celebreality Star for the 2012 People's Choice Awards.

He combined successful knee break and outdated in the US Fodder.

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She had an IVF transfer for a second time in November 2010; however, the procedure did not result in a pregnancy.

When the couple decided to try for a third round of IVF, her doctor recommended a mammogram, which is how she found out she had breast cancer.

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